NFL Week 6 kicks off Thursday night, as the Giants host the Eagles.
Here are the lines for every Week 6 matchup at DraftKings Sportsbook as of Oct. 9.
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(All times ET)
2025 NFL Week 6 Odds
THURSDAY, OCT. 9
Spread: Eagles -7
Moneyline: Eagles -395, Giants +310
Over/Under: 40.5
SUNDAY, OCT. 12
Spread: Broncos -7.5
Moneyline: Broncos -395, Jets +310
Over/Under: 43.5
Spread: Colts -7
Moneyline: Colts -340, Cardinals +270
Over/Under: 46.5
Spread: Cowboys -3
Moneyline: Cowboys -175, Panthers +145
Over/Under: 49.5
Spread: Chargers -4.5
Moneyline: Chargers -225, Dolphins +185
Over/Under: 44.5
Spread: Rams -7.5
Moneyline: Rams -380, Ravens +300
Over/Under: 44.5
Spread: Steelers -5.5
Moneyline: Steelers -258, Browns +210
Over/Under: 37.5
Spread: Patriots -3.5
Moneyline: Patriots -185, Saints +154
Over/Under: 45.5
Spread: Jaguars -1.5
Moneyline: Jaguars -112, Seahawks -108
Over/Under: 47.5
Spread: Raiders -3.5
Moneyline: Raiders -218, Titans +180
Over/Under: 41.5
Spread: Packers -14
Moneyline: Packers -1050, Bengals +675
Over/Under: 44.5
Spread: Buccaneers -3
Moneyline: Buccaneers -162, 49ers +136
Over/Under: 47.5
Spread: Chiefs -2.5
Moneyline: Chiefs -135, Lions +114
Over/Under: 52.5
MONDAY, OCT. 13
Spread: Bills -4.5
Moneyline: Bills -225, Falcons +185
Over/Under: 49.5
Spread: Commanders -4.5
Moneyline: Commanders -225, Bears +185
Over/Under: 49.5
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